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Bupropion (Wellbutrin, Wellbutrin SR, Wellbutrin XR, Zyban)
Monthly Archives of Research Articles
Month
News
Items
Pubmed
Articles
Highlights
August 2003
08.17.03 [103]
08.10.03 [103]
08.03.03 [106]
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July 2003
07.27.03 [71]
07.20.03 [178]
11
June 2003
11
May 2003
13
April 2003
18
March 2003
12
February 2003
15
January 2003
01.26.03
01.19.03
01.12.03
01.05.03
16
stereoisomers (mirror images of same molecule)
•
smoking
INTERACTIONS
:
carbimazole
SFX
:
ballism (movement disorder)
•
liver failure
•
blood disorder
•
hives/rash
•
overdose
•
itching
•
psychosis
TRIALS
:
added to SSRIs [n=28 OL]
•
adult ADHD in cocaine users [n=19 OL]
December 2002
12.29.02
12.22.02
12.15.02
12.08.02
12.01.02
8
smoking
•
erectile dysfunction (rats)
•
bipolar depression
SFX
:
paradoxical
•
REM sleep
November 2002
11.17.02
11.10.02
11.03.02
18
smoking
•
breastfeeding
•
marijuana withdrawal
INTERACTIONS
:
methylphenidate/Ritalin/Concerta
•
P450 genetic variant affects smoking abstinence
•
paroxetine/Paxil
SFX
:
psychomotor performance
•
seizure
•
overdose
•
REM sleep
•
falls in elderly
•
sexual
October 2002
10.20.02
10.13.02
10.06.02
11
smoking
SFX
:
cardiac effects from overdose
TRIALS
:
smoking [n=935 OL]
•
smoking, vs nortriptyline/Pamelor [n=220 DBPC]
•
weight loss and depression [n=384 DBPC]
September 2002
09.29.02
09.22.02
09.01.02
19
for diabetic neuropathy
•
weight loss due to thermogenesis
•
for atopic dermatitis & psoriasis
•
smoking
SFX
:
sexual
•
safety
•
seizures after sniffing
TRIALS
:
for chewing tobacco cessation [n=68 DBPC]
August 2002
08.04.02
12
ADHD adults
•
smoking
•
dopamine transporter
•
nicotinic receptors
TRIALS
:
vs topiramate/Topamax for augmentation in bipolar depression [n=36 SB]
•
smoking [n=50 OL]
•
smoking [n=784 OL]
July 2002
07.28.02
07.21.02
07.14.02
07.07.02
20
drug abuse
•
ADHD
•
smoking
•
in animal model of depression
•
beta-1 receptors
•
memory
INTERACTIONS
SFX
:
seizure
•
overdosage
TRIALS
:
smoking in African Americans [n=600 DBPC]
•
for weight loss [n=327 DBPC]
•
smoking [n=251 PC]
June 2002
15
amfebutamone (alternate name for bupropion)
•
smoking
•
effect on bipolar cycling
SFX
:
psoriasis
TRIALS
:
smoking and schizophrenia [n=32 DBPC]
May 2002
20
drug interactions
•
for amphetamine withdrawal
•
depression relapse prevention
•
smoking cessation
SFX
:
EKG
•
toxicity
•
sexual
•
weight loss
April 2002
14
preventing smoking relapse
•
smoking cessation
INTERACTIONS
:
steroid injections
•
Effexor/Prozac/Paxil
SFX
:
deaths?
•
seizures
•
toxicity
•
erythema multiforme
•
sexual
March 2002
12
February 2002
11
January 2002
11
---ALL 2001---
147
December 2001
4
November 2001
15
[n=number of subjects in study. OL=open label (nonblinded). SB=single-blind. DB=double-blind. PC=placebo control. SFX=side effects]