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Fluoxetine (Prozac, Prozac Weekly, Sarafem)

Monthly Archives of Research Articles

Month	News Items	Pubmed Articles	Highlights
August 2003	08.17.03 [396] 08.10.03 [508] 08.03.03 [475]	click	Click here to go to our six-month Anniversary Issue #26 (08/04/03) of our members-only weekly newsletter!!
July 2003	07.27.03 [393] 07.20.03 [292]	29
June 2003		27
May 2003		38
April 2003		35
March 2003		38
February 2003		29	driving • alcohol withdrawal • OCD • GABA-A receptors • 5HT-1A receptors • poststroke motor function • aggression • neonatal exposure INTERACTIONS: general • cocaine/dopamine • zaprinast • CYP2D6 • haloperidol/Haldol • allopregnanolone SFX: weight gain • sexual • withdrawal • agitation • insomnia • abnormally enlarged breasts (gynecomastia) • prolactin • extrapyramidal • cardiac/QTc
January 2003	01.26.03 01.19.03 01.12.03 01.05.03	30	killing cancer cells: Burkitt lymphoma treatment? • aggression [animal] • cocaine use • borderline personality disorder • in animal model of depression [rat] • selective mutism • brain growth factor needed for antidepressant effect • eating disorder INTERACTIONS: estrogen hormones • olanzapine/Zyprexa • valproic acid/Depakote • tramadol/Ultram SFX: anxiety [rat] • sexual dysfunction in women TRIALS: with olanzapine/Zyprexa for psychotic depression [n=27 OL] • vs psychotherapy [n=450 DBPC] • adult ADHD in cocaine users [n=19 OL]
December 2002	12.29.02 12.22.02 12.15.02 12.08.02 12.01.02	28	fibromyalgia • sweating in social anxiety • OCD • probing mechanisms of action • brain levels of serotonin and norepinephrine (rat) • migraines • genetic predictors of response • stereoselective effects (rat) INTERACTIONS: phencyclidine/PCP and NMDA receptors • P450 effects (rat) • phototherapy • 5HT-2 antagonists (animal) SFX: emotional blunting • sleep, driving performance • rash
November 2002	11.17.02 11.10.02 11.03.02	45	review: premenstrual dysphoric disorder (PMDD) • eating disorders • body dysmorphic disorder • probing the mechanisms of depression response • dual action antidepressants better (rats) • vs turmeric (Curcuma longa) (mice) INTERACTIONS: pharmacokinetics in children • heparin/Lovenox • pimozide/Orap • SFX: review: suicidal ideation • bleeding • seizures (rats) TRIALS: primary care: treatment of cancer-related depression by algorithm [n=35 OLPC] • OCD in children and adolescents [n=43 OLPC] • binge-eating [n=60 DBPC] • premenstrual dysphoric disorder (PMDD) [n=108 OLPC] • autism [n=129 OL] • no effects on child after fetal exposure [n=122 OL]
October 2002	10.20.02 10.13.02 10.06.02	33	speed of onset • postnatal depression and breast milk • depression during pregnancy INTERACTIONS: amantadine in rats • amphetamine SFX: hyponatremia and 2D6 • weight loss in rats • manic sx in adults with learning disabilities TRIALS: vs tianeptine [n=178 DB; n=387 DB] • sleep and anxiety in depression, vs dothiepine [n=125 DB] • pediatric depression [n=219 DBPC] • preventing PTSD relapse [n=131 DBPC]
September 2002	09.29.02 09.22.02 09.08.02 09.01.02	33	blood levels • breast milk • PMDD (premenstrual dysphoric disorder) • adding CBT for OCD • R-fluoxetine • transporter-binding: R-fluoxetine vs escitalopram/Lexapro vs other SSRIs • decrease in impulsive behavior in pigeons • vs St John's wort • personality disorder symptoms INTERACTIONS: oral contraceptives (birth control pills) and unplanned pregnancy SFX: sexual TRIALS: relapse risk: with or without cognitive therapy [n=132 OL] • for depression w/anxiety [n=123 OL] • for PMDD: 10 vs 20 mg [n=260 SBPC] • for depressed methadone maintenance patients [n=49 DBPC]
August 2002	08.25.02 08.11.02 08.04.02	29	pregnancy • prescriptions • cholesterol and response rate • memory • treatment-resistant depression • tics INTERACTIONS: P450 2D6 inhibition • tramadol/Ultram • risperidone/Risperdal SFX: mania • withdrawal symptoms (vs paroxetine/Paxil) TRIALS: depression and anxiety (vs venlafaxine/Effexor) [n=1454 DBPC] • smoking [n=989 DBPC] • vs reboxetine [n=381 DBPC] • augmentation with lithium or desipramine [n=101]
July 2002	07.28.02 07.21.02 07.14.02 07.07.02	39	marketing • PMDD (premenstrual dysphoric disorder) • in atypical antipsychotic-induced weight gain • beta-1 receptors • regulation of serotonin release • serotonin-1A receptors • augmentation with olanzapine/Zyprexa for psychotic depression • augmentation with olanzapine/Zyprexa for treatment-resistant depression • vs sertraline/Zoloft • mania • stress response • for autism • for aggression • augmentation with NMDA antagonists amantadine/Symmetrel and memantine/Ebixa • cocaine dependence INTERACTIONS: Ecstacy/MDMA • olanzapine/Zyprexa • progesterone SFX: sexual • urinary retention • learning • weight TRIALS: vs venlafaxine/Effexor [n=146 DB] • vs venlafaxine/Effexor for depression • clonazepam augmentation [n=50 DBPC] • Prozac Weekly in depression relapse [n=501 DBPC]
June 2002		20	for premenstrual dysphoric disorder • blood levels • predicting response • neuropeptide Y • 5HT1B receptors • for childhood depression INTERACTIONS: loratadine/Claritin • tramadol/Ultram • phentermine/Adipex SFX: sexual • weight loss • extrapyramidal
May 2002		42	suicide prevention • serotonin receptors • estrogen augmentation in perimenopausal depression • effect on cholinesterases • in post-traumatic OCD • versus placebo in brain metabolism • treatment response relates to genetic variability of serotonin transporter INTERACTIONS: codeine • selegiline/Eldepryl • caffeine • risperidone/Risperdal SFX: tremor • serotonin syndrome TRIALS: geriatric depression [n=242 DBPC] • prevention of poststroke depression [n=48, DBPC] • versus St. John's wort [n=70 , DBPC] • anxious depression [n=22 DBPC] • social anxiety disorder [n=60 DBPC]
April 2002		40	comparing SSRIs • for stroke • switching to Prozac Weekly • increase in brain growth factor • itching in polycythemia vera INTERACTIONS: St. John's wort and gingko • ECT • adding bupropion/Wellbutrin SFX: rash • withdrawal • low sodium TRIALS: premenstrual dysphoric disorder • body dysmorphic disorder • PTSD • depression [review]
March 2002		43
February 2002		22
January 2002		52
---ALL 2001---		401
December 2001		22
November 2001		23