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Sertraline (Zoloft)
Monthly Archives of Research Articles
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Pubmed
Articles
Highlights
August 2003
08.17.03 [185]
08.10.03 [179]
08.03.03 [82]
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July 2003
07.27.03 [67]
07.20.03 [90]
16
June 2003
13
May 2003
14
April 2003
11
March 2003
13
February 2003
9
January 2003
01.26.03
01.19.03
01.12.03
01.05.03
4
INTERACTIONS
:
olanzapine/Zyprexa
SFX
:
side effects in 659 people
December 2002
12.29.02
12.22.02
12.15.02
12.08.02
12.01.02
7
augmentation with quetiapine/Seroquel in OCD
•
brain tryptophan and serotonin levels (rats)
INTERACTIONS
:
phototherapy
TRIALS
:
premenstrual dysphoric disorder (PMDD) [n=281 DBPC]
November 2002
11.17.02
11.10.02
11.03.02
16
clinical pharmacokinetics
•
OCD
•
PTSD
•
post-heart attack depression
INTERACTIONS
:
tramadol/Ultram (serotonin syndrome)
SFX
:
acute eosinophilic pneumonia
TRIALS
:
dialysis-induced hypotension and heart rate variability [n=30 OL]
October 2002
10.20.02
10.13.02
10.06.02
20
breast milk levels
•
increases dopamine in rats
•
social anxiety
•
PTSD
•
geriatric depression
•
postpartum depression, breastfeeding
SFX
:
panic, akathisia, dystonia
TRIALS
:
co-occuring depression & alcoholism in adolescents [n=10 DBPC]
•
psychomotor performance in pilots [n=19 DBPC]
•
smoking [n=134 DBPC]
September 2002
09.29.02
09.22.02
09.08.02
09.01.02
15
for premature ejaculation
•
dopamine reuptake
•
vs St John's wort
•
in Huntington's with OCD
•
half-life in adolescents
•
for PMDD (premenstrual dysphoric disorder)
•
splitting pills saves money
•
PTSD
SFX
:
sexual
•
vigilance, vs paroxetine/Paxil
TRIALS
:
PMDD and allopregnanolone levels [n=46 DBPC]
•
depression, vs tianeptine/Stablon [n=212 DB]
•
for chronic stomach problems (functional dyspepsia)
August 2002
08.04.02
12
tics
•
post-heart attack depression
•
SSRIs' mechanism of action: transporter blockade or downregulation
INTERACTIONS
:
P450 2D6 inhibition
SFX
:
cardiac
TRIALS
:
for opiate dependence (with naltrexone/Revia augmentation) [n=13 DBPC]
•
panic disorder [n=544 DBPC]
•
post-heart attack depression [n=369 DBPC]
•
chronic depression [n=161 DBPC]
July 2002
07.28.02
07.21.02
07.14.02
07.07.02
16
memory
•
for postoperative pathological laughter
•
pediatric OCD
•
vs fluoxetine/Prozac
•
geriatric depression
•
autism
INTERACTIONS
:
mianserin + thyroid
SFX
:
urinary incontinence
•
night sweats/diaphoresis
TRIALS
:
for chronic tension headaches [n=50 DBPC]
•
geriatric depression [n=225 OL]
•
for aggression & behavioral problems in Alzheimer's dementia [n=22 DBPC]
•
for depression with alcoholism
•
PTSD [PC]
June 2002
6
OCD
•
PMS
INTERACTIONS
:
SFX
:
serotonin syndrome
•
renal transplant
TRIALS
:
vs psychotherapy for dysthymia (n=707 SB)
•
vs St. John's wort (n=87 DB)
May 2002
20
OCD
•
post-stroke depression
•
in opiate withdrawal
•
effect on cholinesterases
•
blood levels in depression
•
versus reboxetine
•
improving compliance in primary care
•
saving money on pills
SFX
:
vaginal bleeding
•
sexual
•
EKG
TRIALS
:
OCD [n=32 SB]
•
post-traumatic depression [n=82 OL]
•
initial nonresponse in depression [n=1629 DBPC]
•
versus St. John's wort
April 2002
21
comparing SSRIs
•
switching to Prozac Weekly
•
pedophilia
•
versus St. John's wort
•
rheumatoid arthritis
INTERACTIONS
:
carbamazepine/Tegretol and phenytoin/Dilantin
SFX
:
low sodium
•
prolactin and thyroid
March 2002
20
February 2002
9
January 2002
21
---ALL 2001---
179
December 2001
12
November 2001
16
[n=number of subjects in study. OL=open label (nonblinded). SB=single-blind. DB=double-blind. PC=placebo control. SFX=side effects]