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Venlafaxine (Effexor, Effexor XR)

Monthly Archives of Research Articles

Month	News Items	Pubmed Articles	Highlights
August 2003	08.17.03 [61] 08.10.03 [60] 08.03.03 [58]	click	Click here to go to our six-month Anniversary Issue #26 (08/04/03) of our members-only weekly newsletter!!
July 2003	07.27.03 [49] 07.20.03 [12]	9
June 2003		13
May 2003		10
April 2003		8
March 2003		16
February 2003		11
January 2003	01.26.03 01.19.03 01.12.03 01.05.03	12	carbon dioxide-induced anxiety in panic disorder • dual-action antidepressants INTERACTIONS: adding Wellbutrin • olanzapine/Zyprexa • P450 2D6 metabolism SFX: serotonin syndrome • galactorrhea (breast milk production) • weight gain, leptin, and tumor necrosis factor-alpha TRIALS: geriatric depression, vs nortriptyline/Pamelor [n=68 SB]
December 2002	12.29.02 12.22.02 12.15.02 12.08.02 12.01.02	24	dual-action antidepressants • brain processing • blood levels • brain levels of serotonin and norepinephrine (rats) • neuroprotective effects • earlier onset of action • for depression-related physical symptoms • effectiveness in depression and anxiety • quality of life in OCD, vs paroxetine/Paxil • cost-effectiveness, vs SSRIs • for diabetic neuropathy during dialysis INTERACTIONS: mirtazapine/Remeron • overdose SFX: stomach/intestine/GI function • serotonin syndrome • hypokalemia (low potassium) • swollen eyelids TRIALS: review of remission rates for controlled trials in depression, vs SSRIs
November 2002	11.17.02 11.03.02	13	GAD (generalized anxiety disorder) • for hot flashes 12409680 speed of onset for depression and anxiety [review] SFX: immunosuppression • liver damage • creatine kinase in overdose TRIALS: SSRI-resistant depression [n=69 OL] • OCD, vs clomipramine/Anafranil [n=73 SB] • GAD with depression or dysthymia [n=32 OL] • high doses in treatment-resistant depression [n=5 OL]
October 2002	10.20.02 10.13.02 10.06.02	20	review • OCD • and psychotherapy • blood levels • efficacy and onset of action, vs SSRIs • with leukopenia INTERACTIONS: indinavir/Crixivan SFX: SIADH TRIALS: binge eating, obesity [n=35 OL]
September 2002	09.29.02 09.22.02 09.01.02	6	in ADD • norepinephrine in depression INTERACTIONS: ECT • amitriptyline/Elavil & meperidine/Demerol SFX: serotonin syndrome • sexual
August 2002	08.25.02	9	pharmaco-economics • for hot flashes • GAD • for neuropathy • blood levels TRIALS: depression and anxiety (vs fluoxetine/Prozac) [n=1454 DBPC] • treatment-resistant depression [n=73 OL]
July 2002	07.28.02 07.21.02 07.14.02 07.07.02	24	in animal model of depression • blood levels • metabolism • beta-1 receptors • augmentation with NMDA antagonists amantadine and memantine • in liver disease/hepatic encephalopathy • GAD • panic disorder • geriatric depression • neurotransmitters • effects on stress-induced norepinephrine release SFX: withdrawal • delirium • sexual • urinary bladder function • GI symptoms TRIALS: vs fluoxetine/Prozac for depression with anxiety [n=146 DB] • lithium augmentation • vs fluoxetine/Prozac for depression
June 2002		13	rapid onset • costs (vs SSRIs) • sustained release tablets • efficacy of SNRIs • predicting response • GAD INTERACTIONS: TRIALS: vs paroxetine/Paxil for bipolar depression (n=60 SB) • GAD (Cochrane Review)
May 2002		14	OCD • ADD and depression • versus SSRIs • in neuropathic pain INTERACTIONS: dextro-amphetamine • cocaine • propofol • ECT SFX: vaginal bleeding • sexual • glaucoma • serotonin syndrome • asystole TRIALS: GAD [n=1839 DBPC]
April 2002		10	hepatic encephalopathy • GAD • binds to opiate receptors INTERACTIONS: bupropion/Wellbutrin • propafenone/Rhythmol SFX
March 2002		17
February 2002		7
January 2002		11
---ALL 2001---		125
December 2001		6
November 2001		6